Like other fibers, Chitosan is indigestible, and can reduce "transit time", which is the time it takes for foods to pass through the digestive system and out of the body. Therefore, less fats in general, including cholesterol, sterols, fatty acids, and essential fatty acids are available to be absorbed. Dietary fiber is usually deficient in modern diets where foods are more highly processed. Fiber tends to increase stool bulk, hydration and acts as a catalyst for colonic microflora, all of which speed transit time, and produce a softer stool.

A high quality essential fatty acid supplement such as flax seed oil, along with ample supplemental fat soluble nutrients vitamins A, D, E, and K should be taken at a meal apart from Chitosan supplementation. Drink at least 64 oz, or 8 full glasses of pure water a day. Not recommended for children or teenagers.